compound5

Chaz: This looks good.



**//__Johnny Velasquez__//**
The PBr places the hydroxy of an OH to a Br. It's a very efficeint first reagent. The PCC transforms an alcohol into an aldehyde. The Wittig reaction was used to make an alkene double bond, where the carbon nucleophile from PH3P+_CHCH3, when combines with the aldehyde makes the carbon to Carbon double bond alkene and therefore occupying the allylic position.... to do more reaction with NBC. NBS puts a Br atom in each of the allilic position. 4carbons from the wittig added 4 more carbons from the aldehyde to form the octtriene.

Johnny: This is great! A synthsis from just ethyl alcohol in only 6 steps! I see no reason why it wouldn't work. Nice job. Bruce Bondurant

Resources: 1. [] 2. Wikipedia: []
 * Jingwen Huang:**

Jingwen: This is a really nice convergent synthesis from ethanal. I think it is a good approach. The oxidation in scheme 2 should be done with PCC or DMSO/oxalylchloride/triethylamine (Swern oxidation). The use of sodium dichromate and sulfuric acid will take it all the way to the carboxylic acid. I think your aldol condensation is thei best, though. This condensation chemistry from chapter 22 is a powerful synthetic tool. Nice work, Bruce Bondurant

Reference: wikipedia.org
 * Elein Ravelo:**

Elein: This looks good It's a nice use of the chemistry from chapter 10. Bruce Bondurant